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*1. [[Pathology]]. The [[point]] in the [[progress]] of a [[disease]] when an important development or [[change]] takes place which is decisive of recovery or death; the turning-point of a disease for better or worse; also applied to any marked or sudden variation occurring in the progress of a disease and to the [[phenomena]] accompanying it.
*2. [[Astrology]]. Said of a conjunction of the [[planets]] which determines the issue of a disease or critical point in the course of [[events]].
*3. A vitally important or decisive stage in the progress of anything; a [[turning-point]]; also, a [[state]] of affairs in which a decisive [[change]] for better or worse is imminent; now applied esp. to times of difficulty, insecurity, and suspense in [[politics]] or commerce.
*4. [[Judgement]], [[decision]]. Obs.
*5. A point by which to judge; a criterion, token, [[sign]]. Obs
[[Category: General Reference]]